Meet Dr. Anne Wheeler, the new Catalyst Scholar in traumatic brain injury at SickKids

Kids’ brains aren’t adult brains. The injury and recovery processes in a developing brain are distinctly different from those in an adult one. Traumatic injury to a child’s brain can affect neurodevelopmental processes, resulting in unique consequences – how a person thinks and feels, how their body functions, and how their senses work – so it’s critical to understand these differences. Dr. Wheeler is exploring new ways to understand a child’s brain, and how to treat them.
SickKids patient held by SickKids staff member

Dr. Wheeler is exploring new ways to understand a child’s brain, and how to treat them.
Most of us have heard of ‘concussion’. That’s a mild form of TBI. Because TBI ranges in severity, some people recover fully, while others can suffer from long-term disability including cognitive and behavioural disturbances. Dr. Wheeler’s work involves using structural brain imaging to look for biomarkers of TBI, to identify brain damage, inform prognosis, and monitor which treatments work. She identifies biomarkers using magnetic resonance imaging (MRI), which detects subtle microscopic alterations in the brain. At SickKids, she proposes to develop a large sample of MRIs. Applying advanced analysis tools to this sample, combined with analysis of blood markers, could help develop a treatment approach to TBI that is personalized to each child.

Dr. Anne Wheeler completed her PhD at the University of Toronto in the Neurosciences and Mental Health Program at SickKids. She comes to her new role as a Traumatic Brain Injury (TBI) scholar at SickKids from the Translational Imaging Genetics Lab at the Centre for Addiction and Mental Health (CAMH).